Double Genetic Hit: Fragile X Syndrome and Partial Deletion of Protein Patched Homolog 1 Antisense as Cause of Severe Autism Spectrum Disorder

Medicine & Life Sciences

• Patched-1 Receptor 100%
• Fragile X Syndrome 71%
• Autism Spectrum Disorder 57%
• Proteins 20%
• Autistic Disorder 18%
• Intellectual Disability 11%
• Inborn Genetic Diseases 11%
• Genes 9%
• Comorbidity 9%
• Fragile X Mental Retardation Protein 9%
• Maternal Inheritance 7%
• Exome 7%
• Comparative Genomic Hybridization 7%
• Mutation 6%
• Point Mutation 5%
• Diagnostic and Statistical Manual of Mental Disorders 5%
• Appointments and Schedules 5%
• Language 4%
• Anxiety 4%
• Observation 4%
• Psychology 4%
• Phenotype 3%

Social Sciences

• autism 53%
• cause 32%
• genetic disorders 14%
• diagnostic 11%
• comorbidity 11%
• intellectual disability 9%
• present 5%
• mental disorder 4%
• anxiety 2%