TY - GEN
T1 - Determining the scale of image patches using a deep learning approach
AU - Otalora, Sebastian
AU - Perdomo, Oscar
AU - Atzori, Manfredo
AU - Andersson, Mats
AU - Jacobsson, Ludwig
AU - Hedlund, Martin
AU - Muller, Henning
N1 - Funding Information:
This work was partially supported by the Eurostars project E! 9653 SLDESUTO-BOX and by Nvidia.
Publisher Copyright:
© 2018 IEEE.
Copyright:
Copyright 2018 Elsevier B.V., All rights reserved.
PY - 2018/5/23
Y1 - 2018/5/23
N2 - Detecting the scale of histopathology images is important because it allows to exploit various sources of information to train deep learning (DL) models to recognise biological structures of interest. Large open access databases with images exist, such as The Cancer Genome Atlas (TCGA) and PubMed Central but very few models can use such datasets because of the variability of the data in color and scale and a lack of metadata. In this article, we present and compare two deep learning architectures, to detect the scale of histopathology image patches. The approach is evaluated on a patch dataset from whole slide images of the prostate, obtaining a Cohen's kappa coefficient of 0.9897 in the classification of patches with a scale of 5×, 10× and 20×. The good results represent a first step towards magnification detection in histopathology images that can help to solve the problem on more heterogeneous data sources.
AB - Detecting the scale of histopathology images is important because it allows to exploit various sources of information to train deep learning (DL) models to recognise biological structures of interest. Large open access databases with images exist, such as The Cancer Genome Atlas (TCGA) and PubMed Central but very few models can use such datasets because of the variability of the data in color and scale and a lack of metadata. In this article, we present and compare two deep learning architectures, to detect the scale of histopathology image patches. The approach is evaluated on a patch dataset from whole slide images of the prostate, obtaining a Cohen's kappa coefficient of 0.9897 in the classification of patches with a scale of 5×, 10× and 20×. The good results represent a first step towards magnification detection in histopathology images that can help to solve the problem on more heterogeneous data sources.
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U2 - 10.1109/ISBI.2018.8363703
DO - 10.1109/ISBI.2018.8363703
M3 - Conference contribution
AN - SCOPUS:85048099378
T3 - Proceedings - International Symposium on Biomedical Imaging
SP - 843
EP - 846
BT - 2018 IEEE 15th International Symposium on Biomedical Imaging, ISBI 2018
PB - IEEE Computer Society
T2 - 15th IEEE International Symposium on Biomedical Imaging, ISBI 2018
Y2 - 4 April 2018 through 7 April 2018
ER -
