Primary culture of human keratinocytes planted on pig's intestine submucosa

Ángela Ximena Amórtegui, Sandra Rocío Ramírez

Research output: Contribution to journalArticlepeer-review


Tissue engineering, in the fields of skin regeneration, seeks to overcome the limitations associated with the use of immediate auto-grafts, since choosing the donor region of the patient constitutes a risk for the patient himself and is insufficient if the injury that has to be repaired is very large. The use of the pig's small intestine submucosa (SIS) has being proved as a filling biomaterial to treat injuries, because of its special composition, it lowers pain and inflammation since its first application and it favours early mobility to the wounded area. The present study developed a protocol for the primary culture of human keratinocytes from infant foreskins, and used small intestinal submucosa (SIS) like culture substrate. Cellular adherence potential and proliferation capability of the keratinocytes over this substrate was evaluated.

Translated title of the contributionCultivo primario de queratinocitos humanos sembrados en submucosa intestinal porcina
Original languageEnglish (US)
Pages (from-to)8-22
Number of pages15
JournalRevista ciencias de la salud
Issue number3
StatePublished - 2008

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Health(social science)


Dive into the research topics of 'Primary culture of human keratinocytes planted on pig's intestine submucosa'. Together they form a unique fingerprint.

Cite this