Abstract
Background: To report a case of coinfection of Toxoplasma gondii (Tg) and Epstein Barr Virus (EBV) in a diabetic patient with rheumatoid arthritis and immunosuppressive biological therapy.
Case presentation: A 70-year-old female with a history of rheumatoid arthritis on therapy with corticosteroids, methotrexate, and abatacept presented bilateral granulomatous panuveitis associated with retinal necrosis and macular involvement. A diagnostic vitrectomy detected Tg and EBV. Treatment with clindamycin, trimethoprim-sulfamethoxazole, and acyclovir was established, achieving improvement.
Conclusions: Patients undergoing immunosuppressive therapy are at risk of developing opportunistic infections, often presenting with severe and atypical clinical manifestations. In such cases, multiplex polymerase chain reaction is an invaluable diagnostic tool that helps identify the specific pathogens involved. This enables healthcare professionals to make informed treatment decisions and provide targeted therapy for each identified pathogen.
| Translated title of the contribution | La sospecha de coinfección es imperativa en pacientes inmunodeprimidos con sospecha de uveítis infecciosa y respuesta inadecuada al tratamiento: Informe de un caso |
|---|---|
| Original language | English (US) |
| Pages (from-to) | 2548-2552 |
| Number of pages | 5 |
| Journal | Ocular Immunology and Inflammation |
| Volume | 32 |
| Issue number | 10 |
| DOIs | |
| State | Published - Dec 2024 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
-
SDG 3 Good Health and Well-being
All Science Journal Classification (ASJC) codes
- Immunology and Allergy
- Ophthalmology
Fingerprint
Dive into the research topics of 'Coinfection Suspicion is Imperative in Immunosuppressed Patients with Suspected Infectious Uveitis and Inadequate Treatment Response: A Case Report'. Together they form a unique fingerprint.Cite this
- APA
- Author
- BIBTEX
- Harvard
- Standard
- RIS
- Vancouver