'Chymotensin' - An angiotensin like substance released from human plasma by chymotrypsin

H. L. Nolly, R. R. Cabrera, J. C. Fasciolo

Research output: Contribution to journalResearch Articlepeer-review

Abstract

An angiotensin like polypeptide was produced by incubating chymotrypsin with human plasma. This vasoactive substance, provisionally called 'chymotensin' is thermostable, dialyzable and soluble in distilled water, propanol or butanol. Chymotensin increases blood pressure in the rat and displays a vasoconstrictor effect and oxytocic activity on isolated preparations. Chemical and biological characterization to date indicates that this vasoactive polypeptide is angiotensin II.

Original languageEnglish (US)
Pages (from-to)484-487
Number of pages4
JournalActa Physiologica Latino-Americana
Volume24
Issue number5
StatePublished - 1974
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Physiology
  • Pharmacology

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