Changes in oxygenation levels precede changes in amplitude of the EEG in premature infants

Alexander Caicedo; Liesbeth Thewissen; Anne Smits; Gunnar Naulaers; Karel Allegaert; Sabine Van Huffel

doi:10.1007/978-3-319-38810-6_19

Changes in oxygenation levels precede changes in amplitude of the EEG in premature infants

Alexander Caicedo, Liesbeth Thewissen, Anne Smits, Gunnar Naulaers, Karel Allegaert, Sabine Van Huffel

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

Brain function is supported by an appropriate balance between the metabolic demand and the supply of nutrients and oxygen. However, the physiological principles behind the regulation of brain metabolism and demand in premature infants are unknown. Some studies found that changes in hemodynamic variables in this population precede changes in EEG activity; however, these studies only used descriptive statistics. This paper describes the relationship between changes in cerebral oxygenation, assessed by means of near-infrared spectroscopy (NIRS), and changes in EEG, using mathematical methods taken from information dynamics. In a cohort of 35 neonates subjected to sedation by propofol, we quantified the direction of information transfer between brain oxygenation and EEG. The results obtained indicate that, as reported in other studies, changes in NIRS are likely to precede changes in EEG activity.

Original language	English (US)
Pages (from-to)	143-149
Number of pages	7
Journal	Advances in Experimental Medicine and Biology
Volume	923
DOIs	https://doi.org/10.1007/978-3-319-38810-6_19
State	Published - 2016
Event	43rd Annual Meeting of the International Society on Oxygen Transport to Tissue, ISOTT 2015 - Wuhan, China Duration: Jul 11 2015 → Jul 16 2015

All Science Journal Classification (ASJC) codes

General Biochemistry, Genetics and Molecular Biology

Access to Document

10.1007/978-3-319-38810-6_19

Cite this

@article{d18ef7855abd41f8b692c4b36a14fbd8,

title = "Changes in oxygenation levels precede changes in amplitude of the EEG in premature infants",

abstract = "Brain function is supported by an appropriate balance between the metabolic demand and the supply of nutrients and oxygen. However, the physiological principles behind the regulation of brain metabolism and demand in premature infants are unknown. Some studies found that changes in hemodynamic variables in this population precede changes in EEG activity; however, these studies only used descriptive statistics. This paper describes the relationship between changes in cerebral oxygenation, assessed by means of near-infrared spectroscopy (NIRS), and changes in EEG, using mathematical methods taken from information dynamics. In a cohort of 35 neonates subjected to sedation by propofol, we quantified the direction of information transfer between brain oxygenation and EEG. The results obtained indicate that, as reported in other studies, changes in NIRS are likely to precede changes in EEG activity.",

author = "Alexander Caicedo and Liesbeth Thewissen and Anne Smits and Gunnar Naulaers and Karel Allegaert and {Van Huffel}, Sabine",

note = "Publisher Copyright: {\textcopyright} Springer International Publishing Switzerland 2016. Copyright: Copyright 2017 Elsevier B.V., All rights reserved.; 43rd Annual Meeting of the International Society on Oxygen Transport to Tissue, ISOTT 2015 ; Conference date: 11-07-2015 Through 16-07-2015",

year = "2016",

doi = "10.1007/978-3-319-38810-6_19",

language = "English (US)",

volume = "923",

pages = "143--149",

journal = "Advances in Experimental Medicine and Biology",

issn = "0065-2598",

publisher = "Springer New York",

}

TY - JOUR

T1 - Changes in oxygenation levels precede changes in amplitude of the EEG in premature infants

AU - Caicedo, Alexander

AU - Thewissen, Liesbeth

AU - Smits, Anne

AU - Naulaers, Gunnar

AU - Allegaert, Karel

AU - Van Huffel, Sabine

PY - 2016

Y1 - 2016

N2 - Brain function is supported by an appropriate balance between the metabolic demand and the supply of nutrients and oxygen. However, the physiological principles behind the regulation of brain metabolism and demand in premature infants are unknown. Some studies found that changes in hemodynamic variables in this population precede changes in EEG activity; however, these studies only used descriptive statistics. This paper describes the relationship between changes in cerebral oxygenation, assessed by means of near-infrared spectroscopy (NIRS), and changes in EEG, using mathematical methods taken from information dynamics. In a cohort of 35 neonates subjected to sedation by propofol, we quantified the direction of information transfer between brain oxygenation and EEG. The results obtained indicate that, as reported in other studies, changes in NIRS are likely to precede changes in EEG activity.

AB - Brain function is supported by an appropriate balance between the metabolic demand and the supply of nutrients and oxygen. However, the physiological principles behind the regulation of brain metabolism and demand in premature infants are unknown. Some studies found that changes in hemodynamic variables in this population precede changes in EEG activity; however, these studies only used descriptive statistics. This paper describes the relationship between changes in cerebral oxygenation, assessed by means of near-infrared spectroscopy (NIRS), and changes in EEG, using mathematical methods taken from information dynamics. In a cohort of 35 neonates subjected to sedation by propofol, we quantified the direction of information transfer between brain oxygenation and EEG. The results obtained indicate that, as reported in other studies, changes in NIRS are likely to precede changes in EEG activity.

UR - http://www.scopus.com/inward/record.url?scp=84984861362&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84984861362&partnerID=8YFLogxK

U2 - 10.1007/978-3-319-38810-6_19

DO - 10.1007/978-3-319-38810-6_19

M3 - Article

C2 - 27526136

AN - SCOPUS:84984861362

SN - 0065-2598

VL - 923

SP - 143

EP - 149

JO - Advances in Experimental Medicine and Biology

JF - Advances in Experimental Medicine and Biology

T2 - 43rd Annual Meeting of the International Society on Oxygen Transport to Tissue, ISOTT 2015

Y2 - 11 July 2015 through 16 July 2015

ER -

Changes in oxygenation levels precede changes in amplitude of the EEG in premature infants

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this