TY - JOUR
T1 - Cardiovascular disease in the antiphospholipid syndrome
AU - Amaya-Amaya, Jenny
AU - Rojas-Villarraga, Adriana
AU - Anaya, Juan Manuel
N1 - Funding Information:
This work was supported by the School of Medicine and Health Sciences, Universidad del Rosario (ABN011), Bogotá, Colombia.
Publisher Copyright:
© The Author(s) 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.
Copyright:
Copyright 2015 Elsevier B.V., All rights reserved.
PY - 2014/10/8
Y1 - 2014/10/8
N2 - The prevalence of cardiovascular disease (CVD) in antiphospholipid syndrome (APS) varies from one series to another depending on the definition of CVD and tools used for its detection. Atherosclerosis, the usual cause of CVD, starts when the endothelium becomes damaged and is considered to be an autoimmune-inflammatory disease. The excessive cardiovascular events observed in patients with APS are not fully explained by traditional risk factors. Therefore, several novel risk factors contribute to the development of premature CVD and accelerated vascular damage in those patients. Herein, the significance and outcomes of CVD in APS are reviewed.
AB - The prevalence of cardiovascular disease (CVD) in antiphospholipid syndrome (APS) varies from one series to another depending on the definition of CVD and tools used for its detection. Atherosclerosis, the usual cause of CVD, starts when the endothelium becomes damaged and is considered to be an autoimmune-inflammatory disease. The excessive cardiovascular events observed in patients with APS are not fully explained by traditional risk factors. Therefore, several novel risk factors contribute to the development of premature CVD and accelerated vascular damage in those patients. Herein, the significance and outcomes of CVD in APS are reviewed.
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U2 - 10.1177/0961203314540015
DO - 10.1177/0961203314540015
M3 - Research Article
C2 - 25228729
AN - SCOPUS:84908690021
SN - 0961-2033
VL - 23
SP - 1288
EP - 1291
JO - Lupus
JF - Lupus
IS - 12
ER -
