Autonomic symptoms following Zika virus infection

Yhojan Rodríguez; Manuel Rojas; Carolina Ramírez-Santana; Yeny Acosta-Ampudia; Diana M. Monsalve; Juan Manuel Anaya

doi:10.1007/s10286-018-0515-1

Autonomic symptoms following Zika virus infection

Yhojan Rodríguez
, Manuel Rojas
, Carolina Ramírez-Santana
, Yeny Acosta-Ampudia
, Diana M. Monsalve
, Juan Manuel Anaya

School of Medicine and Health Sciences

Research output: Contribution to Journal › Research Article › peer-review

11 Scopus citations

Abstract

Purpose: To determine if autonomic symptoms are associated with previous Zika virus infection. Methods: Case–control study including 35 patients with Zika virus infection without evidence of neurological disease and 105 controls. Symptoms of autonomic dysfunction were assessed with the composite autonomic symptom scale 31 (COMPASS-31). Results: Patients with previous Zika virus infection had significantly higher COMPASS-31 score than controls regardless of age and sex (p = 0.007). The main drivers for the higher scores where orthostatic intolerance (p = 0.003), secretomotor (p = 0.04) and bladder symptoms (p < 0.001). Conclusion: Zika virus infection is associated with autonomic dysfunction. The mechanisms remain to be elucidated.

Original language	English (US)
Pages (from-to)	211-214
Number of pages	4
Journal	Clinical Autonomic Research
Volume	28
Issue number	2
DOIs	https://doi.org/10.1007/s10286-018-0515-1
State	Published - Apr 1 2018

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

All Science Journal Classification (ASJC) codes

Endocrine and Autonomic Systems
Clinical Neurology

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10.1007/s10286-018-0515-1

Cite this

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title = "Autonomic symptoms following Zika virus infection",

abstract = "Purpose: To determine if autonomic symptoms are associated with previous Zika virus infection. Methods: Case–control study including 35 patients with Zika virus infection without evidence of neurological disease and 105 controls. Symptoms of autonomic dysfunction were assessed with the composite autonomic symptom scale 31 (COMPASS-31). Results: Patients with previous Zika virus infection had significantly higher COMPASS-31 score than controls regardless of age and sex (p = 0.007). The main drivers for the higher scores where orthostatic intolerance (p = 0.003), secretomotor (p = 0.04) and bladder symptoms (p < 0.001). Conclusion: Zika virus infection is associated with autonomic dysfunction. The mechanisms remain to be elucidated.",

author = "Yhojan Rodr{\'i}guez and Manuel Rojas and Carolina Ram{\'i}rez-Santana and Yeny Acosta-Ampudia and Monsalve, \{Diana M.\} and Anaya, \{Juan Manuel\}",

note = "Funding Information: Funding source This study was supported by Universidad del Rosario (ABN011), and Colciencias (747-2016), Bogot{\'a}, Colombia. Publisher Copyright: {\textcopyright} 2018, Springer-Verlag GmbH Germany, part of Springer Nature.",

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doi = "10.1007/s10286-018-0515-1",

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TY - JOUR

T1 - Autonomic symptoms following Zika virus infection

AU - Rodríguez, Yhojan

AU - Rojas, Manuel

AU - Ramírez-Santana, Carolina

AU - Acosta-Ampudia, Yeny

AU - Monsalve, Diana M.

AU - Anaya, Juan Manuel

N1 - Funding Information: Funding source This study was supported by Universidad del Rosario (ABN011), and Colciencias (747-2016), Bogotá, Colombia. Publisher Copyright: © 2018, Springer-Verlag GmbH Germany, part of Springer Nature.

PY - 2018/4/1

Y1 - 2018/4/1

N2 - Purpose: To determine if autonomic symptoms are associated with previous Zika virus infection. Methods: Case–control study including 35 patients with Zika virus infection without evidence of neurological disease and 105 controls. Symptoms of autonomic dysfunction were assessed with the composite autonomic symptom scale 31 (COMPASS-31). Results: Patients with previous Zika virus infection had significantly higher COMPASS-31 score than controls regardless of age and sex (p = 0.007). The main drivers for the higher scores where orthostatic intolerance (p = 0.003), secretomotor (p = 0.04) and bladder symptoms (p < 0.001). Conclusion: Zika virus infection is associated with autonomic dysfunction. The mechanisms remain to be elucidated.

AB - Purpose: To determine if autonomic symptoms are associated with previous Zika virus infection. Methods: Case–control study including 35 patients with Zika virus infection without evidence of neurological disease and 105 controls. Symptoms of autonomic dysfunction were assessed with the composite autonomic symptom scale 31 (COMPASS-31). Results: Patients with previous Zika virus infection had significantly higher COMPASS-31 score than controls regardless of age and sex (p = 0.007). The main drivers for the higher scores where orthostatic intolerance (p = 0.003), secretomotor (p = 0.04) and bladder symptoms (p < 0.001). Conclusion: Zika virus infection is associated with autonomic dysfunction. The mechanisms remain to be elucidated.

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EP - 214

JO - Clinical Autonomic Research

JF - Clinical Autonomic Research

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Autonomic symptoms following Zika virus infection

Abstract

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All Science Journal Classification (ASJC) codes

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