Apparent False Lateralization of Seizure Onset by Scalp EEG in Temporal Lobe Epilepsy Associated with Cerebral Cavernous Malformation: A Case Report and Overview

Translated title of the contribution: Aparente falsa lateralización epileptica por EEG en epilepsia del lobulo termporal asociado con malformación cavernomatosa cerebral: reporte de caso y descripción general

Mauricio Orlando Nava Mesa, mariana gaviria, jonathan lopez, Gloria Ortiz‐Guerrero, Jesus Hernan Rodriguez, Ivan Gaona

Research output: Contribution to journalArticle

Abstract

False lateralization of ictal onset by scalp electroencephalogram (EEG) is an infrequent entity that has been reported in patients with mesial temporal lobe epilepsy associated with hippocampal sclerosis (HS). In these cases, a tendency for rapid seizures that spread through the frontal-limbic system and hippocampal commissural pathways to the contralateral hemisphere has been proposed. Cerebral cavernous malformations (CCMs), which constitute a collection of abnormally configured small blood vessels with irregular structures, is a well-defined epilepsy-associated pathology. Their primary association with seizures might be explained either as a result of physiological changes affecting the cerebral cortex immediately surrounding the CCM (an epileptogenic mechanism that is relevant for both, temporal and extratemporal lesions) or as a result of promoting epileptogenicity in remote but anatomo-functionally connected brain regions, a mechanism that is particularly relevant for temporal lobe lesions. To date, there have been only two publications on falsely lateralizing ictal onsets by EEG in temporal cavernoma, but not in other regions. Here, we report a rare case of apparent false lateralization of ictal onset by scalp EEG in a patient with a left medial frontal gyrus cavernoma (supplementary motor area), and discuss some relevant pathophysiological mechanisms of false lateralization.
Translated title of the contributionAparente falsa lateralización epileptica por EEG en epilepsia del lobulo termporal asociado con malformación cavernomatosa cerebral: reporte de caso y descripción general
Original languageEnglish
Pages (from-to)1
Number of pages15
JournalBrain Sciences
Volume9
Issue number584
StatePublished - Aug 24 2020

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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