Anemia aplastica. Tratamento alternativo a transplantacao medular

T. Fonseca; J. Raposo; B. Gomez; J. J.G. D'Oliveira; J. M. Forjaz De Lacerda

Anemia aplastica. Tratamento alternativo a transplantacao medular

Translated title of the contribution: Aplastic anemia - Alternative treatment to bone marrow transplantation

T. Fonseca
, J. Raposo
, B. Gomez
, J. J.G. D'Oliveira
, J. M. Forjaz De Lacerda

Research output: Contribution to Journal › Research Article › peer-review

Abstract

We report a case of a 25-year-old woman, with the diagnosis of severe aplastic anemia without a histocompatible sibling donor for bone marrow transplantation. The patient has been treated successfully with a combination of two immunosuppressive agents, cyclosporine and antilymphocyte globulin, after not responding to primary therapy with corticosteroids and growth factors. She showed a complete response to treatment, with transfusional independence, after a follow-up of 14 months. The pathophysiology of aplastic anemia, the mechanism of action and secondary effects of these treatments are discussed.

Translated title of the contribution	Aplastic anemia - Alternative treatment to bone marrow transplantation
Original language	Portuguese
Pages (from-to)	99-102
Number of pages	4
Journal	Acta Medica Portuguesa
Volume	10
Issue number	1
State	Published - 1997
Externally published	Yes

All Science Journal Classification (ASJC) codes

General Medicine

Cite this

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title = "Anemia aplastica. Tratamento alternativo a transplantacao medular",

abstract = "We report a case of a 25-year-old woman, with the diagnosis of severe aplastic anemia without a histocompatible sibling donor for bone marrow transplantation. The patient has been treated successfully with a combination of two immunosuppressive agents, cyclosporine and antilymphocyte globulin, after not responding to primary therapy with corticosteroids and growth factors. She showed a complete response to treatment, with transfusional independence, after a follow-up of 14 months. The pathophysiology of aplastic anemia, the mechanism of action and secondary effects of these treatments are discussed.",

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T1 - Anemia aplastica. Tratamento alternativo a transplantacao medular

AU - Fonseca, T.

AU - Raposo, J.

AU - Gomez, B.

AU - D'Oliveira, J. J.G.

AU - Forjaz De Lacerda, J. M.

PY - 1997

Y1 - 1997

N2 - We report a case of a 25-year-old woman, with the diagnosis of severe aplastic anemia without a histocompatible sibling donor for bone marrow transplantation. The patient has been treated successfully with a combination of two immunosuppressive agents, cyclosporine and antilymphocyte globulin, after not responding to primary therapy with corticosteroids and growth factors. She showed a complete response to treatment, with transfusional independence, after a follow-up of 14 months. The pathophysiology of aplastic anemia, the mechanism of action and secondary effects of these treatments are discussed.

AB - We report a case of a 25-year-old woman, with the diagnosis of severe aplastic anemia without a histocompatible sibling donor for bone marrow transplantation. The patient has been treated successfully with a combination of two immunosuppressive agents, cyclosporine and antilymphocyte globulin, after not responding to primary therapy with corticosteroids and growth factors. She showed a complete response to treatment, with transfusional independence, after a follow-up of 14 months. The pathophysiology of aplastic anemia, the mechanism of action and secondary effects of these treatments are discussed.

UR - https://www.scopus.com/pages/publications/0030922118

UR - https://www.scopus.com/pages/publications/0030922118#tab=citedBy

M3 - Artículo de Investigación

C2 - 9245186

AN - SCOPUS:0030922118

SN - 0870-399X

VL - 10

SP - 99

EP - 102

JO - Acta Medica Portuguesa

JF - Acta Medica Portuguesa

IS - 1

ER -

Anemia aplastica. Tratamento alternativo a transplantacao medular

Abstract

All Science Journal Classification (ASJC) codes

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