TY - JOUR
T1 - Alta tasa de afectación cardiaca en pacientes colombianos con enfermedad de Kawasaki
AU - Zapata-Castellanos, Aura L.
AU - Eraso, Ruth
AU - Pardo, Aryce L.
AU - Jaramillo, Juan C.
AU - Aguirre, Carlos
AU - Anaya, Juan Manuel
AU - Trujillo, Hugo
N1 - Publisher Copyright:
© 2009 Asociación Colombiana de Reumatología
Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 2009/6/1
Y1 - 2009/6/1
N2 - Kawasaki disease (KD) is a systemic vasculitis, whose main complication is the coronary arteries involvement. This was a retrospective study in which 48 Colombian KD patients were included, and the rate and associated factors to cardiac involvement were investigated. The mean time from the first symptom until the diagnosis was 10.5 days. Cardiac involvement was registered in 13 (27%) patients, of whom 10 presented with coronary disease and 3 with a different cardiac manifestations. Forty-one patients (85.4%) received IV immunoglobulin. By multivariate analysis, the patient's age (OR: 0.91, 95% CI: 0.85–0.98, p = 0.01) and the lapse of time between onset of symptoms and diagnosis (OR: 1.21, 95% CI: 1.05–1.41, p = 0.01) were associated factors influencing cardiac involvement and coronary disease, respectively. The high rate of cardiac compromise in Colombian patients agrees with that observed in other Latin American populations.
AB - Kawasaki disease (KD) is a systemic vasculitis, whose main complication is the coronary arteries involvement. This was a retrospective study in which 48 Colombian KD patients were included, and the rate and associated factors to cardiac involvement were investigated. The mean time from the first symptom until the diagnosis was 10.5 days. Cardiac involvement was registered in 13 (27%) patients, of whom 10 presented with coronary disease and 3 with a different cardiac manifestations. Forty-one patients (85.4%) received IV immunoglobulin. By multivariate analysis, the patient's age (OR: 0.91, 95% CI: 0.85–0.98, p = 0.01) and the lapse of time between onset of symptoms and diagnosis (OR: 1.21, 95% CI: 1.05–1.41, p = 0.01) were associated factors influencing cardiac involvement and coronary disease, respectively. The high rate of cardiac compromise in Colombian patients agrees with that observed in other Latin American populations.
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U2 - 10.1016/S0121-8123(09)70110-0
DO - 10.1016/S0121-8123(09)70110-0
M3 - Artículo de Investigación
AN - SCOPUS:85026320618
SN - 0121-8123
VL - 16
SP - 132
EP - 137
JO - Revista Colombiana de Reumatologia
JF - Revista Colombiana de Reumatologia
IS - 2
ER -