A new look into uveitis in Colombia: changes in distribution patterns and clinical characteristics over the last 25 years

Diego Polanía; Juliana Reyes-Guanes; William Rojas-Carabali; Daniella Pardo-Pizza; Doménico Barraquer-Lopez; Carlos Cifuentes-González; Natalia Neira-Segura; Alejandra de-la-Torre

doi:10.1007/s00417-022-05796-2

A new look into uveitis in Colombia: changes in distribution patterns and clinical characteristics over the last 25 years

Diego Polanía, Juliana Reyes-Guanes, William Rojas-Carabali, Daniella Pardo-Pizza, Doménico Barraquer-Lopez, Carlos Cifuentes-González, Natalia Neira-Segura, Alejandra de-la-Torre

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

PURPOSE: To describe the distribution patterns and clinical characteristics of patients diagnosed with uveitis at a specialized uveitis center in Bogotá, Colombia, from 2013 to 2021 and compare these patterns with the previously reported between 1996 and 2006.

METHODS: We performed an observational descriptive cross-sectional study systematically reviewing clinical records of patients attending between 2013 and 2021. Data were analyzed and compared with previous reports.

RESULTS: Of the 489 patients with uveitis, 310 were females (63.4%). The mean age of onset was 38.7, with a range between 1 and 83 years. Bilateral (52.8%), anterior (45.8%), non-granulomatous (90.8%), and recurrent (47.6%) were the most common types of uveitis found in our population sample. The most common cause of uveitis in this study was idiopathic, followed by toxoplasmosis and HLA-B27 + associated uveitis, which differs from the previous Colombian study where ocular toxoplasmosis was the most frequent cause. This highlights a significant shift from infectious etiologies to more immune-mediated processes as the cause of uveitis in Colombia nowadays.

CONCLUSION: The results of this study provide a comparison between the clinical patterns of presentation of uveitis from 1996 to 2006 and the patterns observed from 2013 to 2021, enhancing awareness about the changing dynamics of uveitis in Colombia to guide a better understanding of the diagnosis, classification, and correlation with other systemic conditions of the disease.

Translated title of the contribution	Una nueva mirada a la uveítis en Colombia: cambios en los patrones de distribución y características clínicas en los últimos 25 años
Original language	English (US)
Journal	Albrecht von Graefes Archiv für Klinische und Experimentelle Ophthalmologie
Issue number	2022
DOIs	https://doi.org/10.1007/s00417-022-05796-2
State	E-pub ahead of print - Aug 22 2022

All Science Journal Classification (ASJC) codes

Ophthalmology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1007/s00417-022-05796-2

Cite this

Polanía, D., Reyes-Guanes, J., Rojas-Carabali, W., Pardo-Pizza, D., Barraquer-Lopez, D., Cifuentes-González, C., Neira-Segura, N., & de-la-Torre, A. (2022). A new look into uveitis in Colombia: changes in distribution patterns and clinical characteristics over the last 25 years. Albrecht von Graefes Archiv für Klinische und Experimentelle Ophthalmologie, (2022). Advance online publication. https://doi.org/10.1007/s00417-022-05796-2

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abstract = "PURPOSE: To describe the distribution patterns and clinical characteristics of patients diagnosed with uveitis at a specialized uveitis center in Bogot{\'a}, Colombia, from 2013 to 2021 and compare these patterns with the previously reported between 1996 and 2006.METHODS: We performed an observational descriptive cross-sectional study systematically reviewing clinical records of patients attending between 2013 and 2021. Data were analyzed and compared with previous reports.RESULTS: Of the 489 patients with uveitis, 310 were females (63.4%). The mean age of onset was 38.7, with a range between 1 and 83 years. Bilateral (52.8%), anterior (45.8%), non-granulomatous (90.8%), and recurrent (47.6%) were the most common types of uveitis found in our population sample. The most common cause of uveitis in this study was idiopathic, followed by toxoplasmosis and HLA-B27 + associated uveitis, which differs from the previous Colombian study where ocular toxoplasmosis was the most frequent cause. This highlights a significant shift from infectious etiologies to more immune-mediated processes as the cause of uveitis in Colombia nowadays.CONCLUSION: The results of this study provide a comparison between the clinical patterns of presentation of uveitis from 1996 to 2006 and the patterns observed from 2013 to 2021, enhancing awareness about the changing dynamics of uveitis in Colombia to guide a better understanding of the diagnosis, classification, and correlation with other systemic conditions of the disease.",

author = "Diego Polan{\'i}a and Juliana Reyes-Guanes and William Rojas-Carabali and Daniella Pardo-Pizza and Dom{\'e}nico Barraquer-Lopez and Carlos Cifuentes-Gonz{\'a}lez and Natalia Neira-Segura and Alejandra de-la-Torre",

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Polanía, D, Reyes-Guanes, J, Rojas-Carabali, W, Pardo-Pizza, D, Barraquer-Lopez, D, Cifuentes-González, C, Neira-Segura, N & de-la-Torre, A 2022, 'A new look into uveitis in Colombia: changes in distribution patterns and clinical characteristics over the last 25 years', Albrecht von Graefes Archiv für Klinische und Experimentelle Ophthalmologie, no. 2022. https://doi.org/10.1007/s00417-022-05796-2

TY - JOUR

T1 - A new look into uveitis in Colombia: changes in distribution patterns and clinical characteristics over the last 25 years

AU - Polanía, Diego

AU - Reyes-Guanes, Juliana

AU - Rojas-Carabali, William

AU - Pardo-Pizza, Daniella

AU - Barraquer-Lopez, Doménico

AU - Cifuentes-González, Carlos

AU - Neira-Segura, Natalia

AU - de-la-Torre, Alejandra

PY - 2022/8/22

Y1 - 2022/8/22

N2 - PURPOSE: To describe the distribution patterns and clinical characteristics of patients diagnosed with uveitis at a specialized uveitis center in Bogotá, Colombia, from 2013 to 2021 and compare these patterns with the previously reported between 1996 and 2006.METHODS: We performed an observational descriptive cross-sectional study systematically reviewing clinical records of patients attending between 2013 and 2021. Data were analyzed and compared with previous reports.RESULTS: Of the 489 patients with uveitis, 310 were females (63.4%). The mean age of onset was 38.7, with a range between 1 and 83 years. Bilateral (52.8%), anterior (45.8%), non-granulomatous (90.8%), and recurrent (47.6%) were the most common types of uveitis found in our population sample. The most common cause of uveitis in this study was idiopathic, followed by toxoplasmosis and HLA-B27 + associated uveitis, which differs from the previous Colombian study where ocular toxoplasmosis was the most frequent cause. This highlights a significant shift from infectious etiologies to more immune-mediated processes as the cause of uveitis in Colombia nowadays.CONCLUSION: The results of this study provide a comparison between the clinical patterns of presentation of uveitis from 1996 to 2006 and the patterns observed from 2013 to 2021, enhancing awareness about the changing dynamics of uveitis in Colombia to guide a better understanding of the diagnosis, classification, and correlation with other systemic conditions of the disease.

AB - PURPOSE: To describe the distribution patterns and clinical characteristics of patients diagnosed with uveitis at a specialized uveitis center in Bogotá, Colombia, from 2013 to 2021 and compare these patterns with the previously reported between 1996 and 2006.METHODS: We performed an observational descriptive cross-sectional study systematically reviewing clinical records of patients attending between 2013 and 2021. Data were analyzed and compared with previous reports.RESULTS: Of the 489 patients with uveitis, 310 were females (63.4%). The mean age of onset was 38.7, with a range between 1 and 83 years. Bilateral (52.8%), anterior (45.8%), non-granulomatous (90.8%), and recurrent (47.6%) were the most common types of uveitis found in our population sample. The most common cause of uveitis in this study was idiopathic, followed by toxoplasmosis and HLA-B27 + associated uveitis, which differs from the previous Colombian study where ocular toxoplasmosis was the most frequent cause. This highlights a significant shift from infectious etiologies to more immune-mediated processes as the cause of uveitis in Colombia nowadays.CONCLUSION: The results of this study provide a comparison between the clinical patterns of presentation of uveitis from 1996 to 2006 and the patterns observed from 2013 to 2021, enhancing awareness about the changing dynamics of uveitis in Colombia to guide a better understanding of the diagnosis, classification, and correlation with other systemic conditions of the disease.

U2 - 10.1007/s00417-022-05796-2

DO - 10.1007/s00417-022-05796-2

M3 - Article

C2 - 35994112

SN - 0065-6100

JO - Albrecht von Graefes Archiv für Klinische und Experimentelle Ophthalmologie

JF - Albrecht von Graefes Archiv für Klinische und Experimentelle Ophthalmologie

IS - 2022

ER -

Polanía D, Reyes-Guanes J, Rojas-Carabali W, Pardo-Pizza D, Barraquer-Lopez D, Cifuentes-González C et al. A new look into uveitis in Colombia: changes in distribution patterns and clinical characteristics over the last 25 years. Albrecht von Graefes Archiv für Klinische und Experimentelle Ophthalmologie. 2022 Aug 22;(2022). Epub 2022 Aug 22. doi: 10.1007/s00417-022-05796-2