A Latin American consensus meeting on the essentials of mixed pain

Mariano Fernandez-Fairen, Carlos Alberto Calderón-Ospina, Juythel Chen, Manuel Duarte Vega, Freddy Fernández-Villacorta, Felipe Gómez-García, Leonardo López-Almejo, Alfredo Manzano-García, Eduardo Hernández-Méndez Villamil, Camilo Partezani Helito, Delia Ruiz-Rodríguez, Guillermo Salas-Morales, Alfredo Servin-Caamaño, Argelia Lara-Solares, Marcelo Puello-Vales, Grisell Vargas-Schaffer

Research output: Contribution to journalResearch Articlepeer-review

2 Scopus citations


Objectives: The term “mixed pain” has been established when a mixture of different pain components (e.g. nociceptive, neuropathic, and nociplastic) are present. It has gained more and more acceptance amongst pain experts worldwide, but many questions around the concept of mixed pain are still unsolved. The sensation of pain is very personal. Cultural, social, personal experiences, idiomatic, and taxonomic differences should be taken into account during pain assessment. Therefore, a Latin American consensus committee was formed to further elaborate the essentials of mixed pain, focusing on the specific characteristics of the Latin American population. Methods: The current approach was based on a systematic literature search and review carried out in Medline. Eight topics about the definition, diagnosis, and treatment of mixed pain were discussed and voted for by a Latin American consensus committee and recommendations were expressed. Results: At the end of the meeting a total of 14 voting sheets were collected. The full consensus was obtained for 21 of 25 recommendations (15 strong agreement and 6 unanimous agreement) formulated for the above described 8 topics (7 of the 8 topics had for all questions at least a strong agreement − 1 topic had no agreement for all 4 questions). Conclusion: In a subject as complex as mixed pain, a consensus has been reached among Latin American specialists on points related to the definition and essence of this pain, its diagnosis and treatment. Recommendations for diagnosis and treatment of mixed pain in Latin America were raised.

Original languageEnglish (US)
Pages (from-to)451-466
Number of pages16
JournalCurrent Medical Research and Opinion
Issue number3
StatePublished - 2023

All Science Journal Classification (ASJC) codes

  • General Medicine


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