Radioresistance and tumour microenvironment: Effect of expression of 135b and 200c miRNAs on glioblastoma-derived cells under hypoxic conditions.

This work is expected to provide knowledge on some of the molecular mechanisms that may be affecting the cellular molecular mechanisms that may be affecting the cellular response to ionizing radiation, and the role of the ionizing radiation, and the role played by the tumor microenvironment in the regulation of these mechanisms. regulation of these mechanisms. In this way, the aim is to identify possible to identify possible therapeutic targets to increase the sensitivity of tumors to radiotherapy. radiotherapy. Likewise, with the development of this project, the idea of which arose from the
Biochemistry Research Semillero (SiBio), the aim is that medical students of the University of Rosario students of the Universidad del Rosario to acquire experience in the area of basic biomedical basic biomedical research, as a way to further strengthen their training as health professi.onals. their training as health professionals, allowing them to participate in the generation of new knowledge the generation of new knowledge applicable to their future medical practice in an area still underdeveloped in our country.