Neuropsychiatric effects with the use of levetiracetam : a systematic review.

Project: Research Project

Project Details


Currently, higher levels of evidence are needed to characterize whether there are neuropsychiatric adverse effects associated with the use of levetiracetam in adults with epilepsy. For this reason, we will conduct a systematic review evaluating the occurrence of neuropsychiatric symptoms such as anxiety, depression, cognitive dysfunction, memory disorders, irritability, aggressiveness, impulsivity, behavioral disorders, suicidality, daytime sleepiness, and psychosis associated with levetiracetam use in adults with epilepsy without previously diagnosed psychiatric disorders. The search will be conducted in PubMed, Embase and Web of Science. Only clinical trials, observational studies, case reports and case series will be included. Quality assessment will be performed using the JBI critical appraisal tools.


levetiracetam, sintomas psiquiátricos, efectos adversos
Short titleefectos adversos del levetiracetam
Effective start/end date4/15/217/15/23

UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Main Funding Source

  • Installed Capacity (Academic Unit)


  • Bogotá D.C.


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