Molecular epidemiology, genomics, population genetics analysis and pathogenesis of the members of the Cryptococcus neoformans and C. gattii species complexes and other fungal species of clinical importance

  • Meyer, Wieland, University of Sydney, (PI)
  • Firacative, Carolina (CoI)
  • Trilles, Luciana, Fundação Oswaldo Cruz, (CoI)
  • Escandón, Patricia, Instituto Nacional de Salud, Bogotá, Colombia,, (CoI)

Project: Research project

Project Details


The rising incidence of cryptococcosis and other mycoses, which can be life-threatening infections affecting both immunocompromised and immunocompetent humans and animals, together with the emergence of outbreaks of infection, highlight the need of an increased and constant vigilance of Cryptococcus neoformans and C. gattii and other clinically important fungi. This ongoing project 1) evaluates new alternative methodologies for the rapid and accurate identification of fungal pathogens; 2) assesses the utility of vertebrate and invertebrate models of infection to study fungal pathogenesis and virulence factors and to screen for strains with different levels of virulence; and 3) applies different molecular approaches to understand the epidemiology of different mycosis, and the differences regarding the genetic diversity, virulence and antifungal susceptibility between and within subtypes and species. Being part of an ongoing research collaboration among different institutions, that continuously study the epidemiology, genetics and pathogenesis of medically important yeasts and molds strongly contribute to our knowledge about the regional and global spread of fungal species and the epidemiology of different mycoses.
Effective start/end date6/1/185/31/20


  • 1 Participation in conference
  • 1 Hosting an academic visitor
  • 1 Membership of board
  • 1 Oral presentation

Wieland Meyer

Carolina Firacative (Host)
Jul 12 2018Jul 13 2018

Activity: Host visitor typesHosting an academic visitor

20th Congress of the International Society for Human and Animal Mycology

Carolina Firacative (Participant)
Jun 30 2018Jul 4 2018

Activity: Attendance typesParticipation in conference