Project Details
Description
General objective: Identify molecular variants in genes related to the etiology of gliomas in a sample of Colombian patients and determine their frequency and impact on clinical classification.
Specific objectives
1. Analyze all the genes proposed by the new 2021 WHO classification in the sample of gliomas from Colombian patients, in order to identify their mutational profile and classification.
2. Determine population-genetic parameters, such as allelic frequency, genotype, and Hardy-Weinberg equilibrium from the molecular results obtained from the gliomas of Colombian patients.
3.Compare and correlate the clinical classification given by the treating physicians of the patients and the classification obtained by following the 2021 WHO guidelines.
Specific objectives
1. Analyze all the genes proposed by the new 2021 WHO classification in the sample of gliomas from Colombian patients, in order to identify their mutational profile and classification.
2. Determine population-genetic parameters, such as allelic frequency, genotype, and Hardy-Weinberg equilibrium from the molecular results obtained from the gliomas of Colombian patients.
3.Compare and correlate the clinical classification given by the treating physicians of the patients and the classification obtained by following the 2021 WHO guidelines.
Keywords
Gliomas. MLPA, molecular variants, allele frequency, genotypic frequency
| Status | Active |
|---|---|
| Effective start/end date | 2/1/23 → 2/1/24 |
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):
Main Funding Source
- Competitive Funds
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