Large-scale genetic analysis for the identification of molecular variants potentially related to the course of relapsing-remitting multiple sclerosis, a multicentre study in a Colombian population.

Project: Research Project

Project Details

Description

Multiple sclerosis (MS) is a chronic, demyelinating, autoimmune disease of the central nervous system, which until a few years ago was classified only according to its phenotype (relapsing-remitting (RR), primary (PP) and secondary progressive (SP)); however, there is a subgroup of RRMS patients with an aggressive disease course due to frequent and severe relapses, incomplete recovery, rapid and permanent accumulation of disability, which has been called aggressive-course MS. To date, clinico-demographic factors related to the disease course are known, but there are few associations with genetic markers or variants that determine the aggressive course and additionally, most studies are in European ancestries.

Keywords

clerosis, autoimmune disease
StatusActive
Effective start/end date11/1/2310/31/24

UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Main Funding Source

  • International

Location

  • Bogotá D.C.
  • Medellín
  • Armenia
  • Manizales
  • Pereira
  • Popayán
  • Santander
  • Región Caribe
  • Cali

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