Activities per year
Project Details
Description
will classify according to their radius-resistance by developing survival curves. Crossing the information of the metabolomic profile and the survival curves, the relationship between metabolic expression profiles and radio-resistance will be established in order to determine the metabolic footprint that allows identifying a patient with a radioresistant tumor.
At the same time, physical simulations will be carried out on the Geant4 platform to establish the optimal physical parameters (material, size, concentration, radiation dose delivered to the tissue) of the possible nanoparticles to be used as radiosensitizers, based on the characteristics of nanoparticles already marketed or undergoing experimentation for this or other purposes. Finally, samples will be selected from patients who have shown radioresistance profiles and the degree of increase in the effectiveness of radiotherapy will be tested in vitro, comparing the survival curves of the sample with and without nanoparticles.
Translated with www.DeepL.com/Translator
Commitments / Obligations
1. Publicación de al menos dos artículos científicos en revistas indexadas internacionalmente.
2. Presentación de ponencias o posters en dos congresos internacionales que cubran temática de radioterapia y/o radiobiología (congresos de la ALATRO, ASTRO o ESTRO).
Productos de formación esperados
1. Articulación de los estudiantes de maestría como jóvenes investigadores de la escuela de Medicina y Ciencias de la Salud.
2. Desarrollo de las actividades académicas en investigación de un estudiante de pregrado en Medicina de último año, cursando la opción de grado co-terminal: Maestría en Epidemiología.
3. Fortalecimiento de las actividades del Semillero de Investigación en Bioquímica, Cáncer y Radiobiología (SiBio) de la EMCS, Universidad del Rosario.
4. Desarrollo de dos tesis de estudiantes de maestría: Un estudiante del programa de Maestría de Ingeniería Biomédica de la Universidad del Rosario y un estudiante de la Maestría en Física Médica de la Universidad Nacional de Colombia.
Status | Finished |
---|---|
Effective start/end date | 3/20/19 → 11/10/22 |
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):
Main Funding Source
- Competitive Funds
Fingerprint
Prizes
-
Premio Carlos Moreno Benavides del Centro Neurovitae - Categoría: Proyecto en Curso
Ondo Mendez, Alejandro Oyono (Recipient), Mar 26 2022
Prize
File
Activities
- 4 Oral presentation
-
Development of green-yellow fluorescent boron-doped carbon dots as a base structure for future construction of potential cancer theranostic nanoplatform
Sergio Alejandro Barragán (Organizer), Michelle Dahyana Soto Florido (Organizer), Paula Andrea Wilches Castellanos (Organizer), Alejandro Oyono Ondo Mendez (Organizer) & Diana Consuelo Rodriguez Burbano (Organizer)
Oct 27 2022Activity: Talk types › Oral presentation
-
DESARROLLO DE UNA NANOPLATAFORMA BASADA EN PUNTOS DE CARBONO DOPADA CON IONES LANTÁNIDOS COMO UN AGENTE RADIOSENSIBILIZADOR EN EL TRATAMIENTO DE GLIOBLASTOMA EN UN MODELO IN VITRO
Mayerly Natalia Ochoa Paipilla (Organizer), Diana Consuelo Rodriguez Burbano (Organizer) & Alejandro Oyono Ondo Mendez (Organizer)
Oct 4 2022Activity: Talk types › Oral presentation
-
Development of Green-Yellow Fluorescent Boron-Doped Carbon Dots as a Base Structure for Future Construction of Potential Cancer Theranostic Nanoplatform
Diana Consuelo Rodriguez Burbano (Speaker), Sergio Alejandro Barragán (Keynote speaker), Michelle Dahyana Soto Florido (Speaker), Paula Andrea Wilches Castellanos (Speaker) & Alejandro Oyono Ondo Mendez (Speaker)
Oct 24 2022 → Oct 28 2022Activity: Talk types › Oral presentation