Project Details
Description
The aim of this study is to evaluate telomerase expression and activity during the in vitro differentiation of human mesenchymal stem cells (hMSCs) into cardiomyocytes. Temporal changes in telomerase activity, TERT gene expression, and additional markers associated with pluripotency, cardiac differentiation, and cellular senescence will be analyzed using molecular and biochemical approaches. Furthermore, the relationship between telomerase activity, cell proliferation, genomic stability, and the efficiency of cardiomyogenic differentiation will be investigated. The findings are expected to provide mechanistic insights into the role of telomerase in cardiac regeneration and support the development of stem cell-based regenerative therapies for cardiovascular diseases.
| Status | Finished |
|---|---|
| Effective start/end date | 4/1/07 → 9/30/08 |
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
Main Funding Source
- Installed Capacity (Academic Unit)
Location
- Región Centro Oriente
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