Development of a radiosensitizing nanoplatform based on carbon dots doped with lanthanides for radiotherapy.

Radiotherapy, widely used in cancer treatment, uses ionizing radiation to eradicate the tumor.

In the face of radio resistance, radiosensitization strategies using nanoparticles have emerged to optimize treatment and reduce its toxicity.

Despite the promising results, this translational research remains essentially preclinical.

The project combines the experience of three laboratories to test the radiosensitizing power of nanocompounds called carbon dots, namely: the experience in synthesis of nanocomposites of the Department of Chemistry and Biochemistry of Concordia University (Canada), the experience in radio awareness from the TIRO laboratory of the University of the Côte d'Azur (France), and research in nanotechnology applied to medicine from the Faculty of Medicine and Health of the University of Rosario (Colombia).

This project will promote the mobility of postgraduate students from the three universities over a period of 24 months and will improve their knowledge in nanotechnology, through the complementarity of skills and cultures of the French-speaking twin laboratories.