The programmed cell death in the human corneal endothelium has been associated with metabolic changes, mechanical stress, endotoxins and nutrient deprivation. In these processes, calcium channels play a primary role, particularly related to changes in membrane potential and ionic currents associated with the induction of apoptosis. In addition, it has recently been shown that KCa and Ca2+ channels, alone or in association, play an important role in proliferation and migration of various cell types. Detailed research into the expression of genes related to proteins that function as ion channels in apoptosis and migration would be very useful in better characterizing the pathophysiology of the endothelium.
|Effective start/end date||3/1/17 → 3/1/19|
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):
Main Funding Source
- Installed Capacity (Academic Unit)
- Bogotá D.C.
Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.