Atypical characteristics of Anterior Uveitis in recurrent polychondritis: A study of series cases

Recurrent polychondritis (RP) is a multisystem inflammatory disease characterized by the destruction of cartilage structures and tissues rich in proteoglycans. Within its wide spectrum of clinical manifestations, which includes destruction of the auricle and nasal cartilage, associated with laryngeal chondritis, a significant percentage of ocular involvement is highlighted, including episcleritis and scleritis, as well as non-granulomatous anterior uveitis; entity that up to now, has only reported 2 cases with recurrent uveitis and one of bilateral chronic uveitis.
Based on what was previously described, a series of cases is carried out that describes 4 patients with various clinical presentations of recurrent polychondritis associated with ophthalmological manifestations that include bilateral chronic anterior uveitis and recurrent anterior uveitis; entities accompanied by underlying inflammatory pathologies and their poor control.
According to the analysis of each patient, it was determined that RP is a difficult entity to diagnose due to its multiple clinical presentations, additionally, it has been strongly associated with other diseases such as rheumatoid arthritis, systemic lupus erythematosus and vasculitis, which make it even more difficult to its recognition to consider it as an etiology of the ocular manifestations. On the other hand, although there is greater certainty in the management of scleritis and episcleritis in RP, there are very few studies regarding the therapy of anterior uveitis in order to prevent its recurrences; Therefore, this series of cases opens the possibility of carrying out a long-term study for its management.

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