Projects per year
Organization profile
Organization profile
The Seedbed for Research in Biochemistry, Cancer and Radiobiology (SiBio) is a learning group made up of undergraduate and graduate students in the areas of biological and health sciences, and teachers from the School of Medicine and Health Sciences. It is part of the research system of the University of Rosario, through its association with the Clinical Research group and its registration with the Research and Innovation Directorate of the University of Rosario.
SiBio allows students to enter the world of translational research, proposing and developing research projects that incorporate techniques of Cell and Molecular Biology, Classical Biochemistry and Biochemistry of the latest generation (such as Metabolomics)aimed at optimising cancer diagnosis and treatment strategies, and at exploring new tools for cancer risk assessment. Also, thanks to collaboration with other EMCS research incubators, we explored the use of nanotechnology and other omic tools (genomics, transcriptomics) for solving health problems.
Research Lines: Determination of metabolomic profiles of non-communicable diseases, mainly cancer, and use of nanomaterials aimed at optimizing diagnostic and treatment strategies.
Objectives:
- Develop in students competences related to the different stages of biomedical research and the scientific method. Encourage students to be responsible and organize teamwork in order to carry out research projects.
- To investigate the effect of tumour microenvironments on cellular response and changes in the metabolism of cancer cells to ionizing radiation, to study tumor resistance to radiation therapy to optimize current cancer treatments.
- To explore metabolic profiles of different types of cancers to evaluate different risk factors, prognosis and treatment with a translational approach.
- To investigate the biological effect of nanomaterials and their possible application for the optimization of methods of diagnosis and treatment of non-communicable diseases, mainly cancer.
Organization profile
The Seedbed for Research in Biochemistry, Cancer and Radiobiology (SiBio) is a learning group made up of undergraduate and graduate students in the areas of biological and health sciences, and teachers from the School of Medicine and Health Sciences. It is part of the research system of the University of Rosario, through its association with the Clinical Research group and its registration with the Research and Innovation Directorate of the University of Rosario.
SiBio allows students to enter the world of translational research, proposing and developing research projects that incorporate techniques of Cell and Molecular Biology, Classical Biochemistry and Biochemistry of the latest generation (such as Metabolomics)aimed at optimising cancer diagnosis and treatment strategies, and at exploring new tools for cancer risk assessment. Also, thanks to collaboration with other EMCS research incubators, we explored the use of nanotechnology and other omic tools (genomics, transcriptomics) for solving health problems.
Research Lines: Determination of metabolomic profiles of non-communicable diseases, mainly cancer, and use of nanomaterials aimed at optimizing diagnostic and treatment strategies.
Objectives:
- Develop in students competences related to the different stages of biomedical research and the scientific method. Encourage students to be responsible and organize teamwork in order to carry out research projects.
- To investigate the effect of tumour microenvironments on cellular response and changes in the metabolism of cancer cells to ionizing radiation, to study tumor resistance to radiation therapy to optimize current cancer treatments.
- To explore metabolic profiles of different types of cancers to evaluate different risk factors, prognosis and treatment with a translational approach.
- To investigate the biological effect of nanomaterials and their possible application for the optimization of methods of diagnosis and treatment of non-communicable diseases, mainly cancer.
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Collaborations and top research areas from the last five years
Projects
- 1 Finished
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Modification of PEG-based polymeric scaffolds by incorporation of carbon dots and nanohydroxyapatite for bone tissue regeneration applications.
Munera Ramírez, M. C. (PI), Rodriguez Burbano, D. C. (CoI) & Ondo Mendez, A. O. (CoI)
1/17/22 → 12/31/22
Project: Research Project
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Integrating molecular profiling into glioma diagnosis: implications of the WHO-CNS5-2021 classification of adult-type diffuse gliomas in Colombian patients
Echeverría, O., Patiño-Aldana, A. F., Chinchilla, A. M., Contreras, N., Peralta, S., Caballero, N., Tovar, H. V., Palacio, J. M., Uribe, V., Mineo-Pachón, M., Velandia, F., Castillo, W. M. R., Valero, N., Silgado-Guzmán, D. F., Ondo-Mendez, A. & Fonseca-Mendoza, D. J., 2026, In: Frontiers in Neurology. 16, 1691983.Research output: Contribution to Journal › Research Article › peer-review
Open Access1 Link opens in a new tab Scopus citations -
Análisis metabolómico de cáncer de seno en pacientes colombianas: exploración de firmas moleculares en distintos subtipos y estadios
Venegas, M. S., León, L., Pardo-Rodriguez, D., Hernandez Rodriguez, A. D. P., Claros Ospina, A. G., Cortes-Guerra, D., López-Molina, G., Ramirez Prieto, J., Alberto-Camargo, J., Rubiano, W., Cala Molina, M. & Ondo Mendez, A. O., Nov 4 2025.Research output: Knowledge networks › Poster
Open Access -
Evaluation of Carbon-Based Fluorescent Nanoparticles as Potential Photosensitizers: Biological and Electrochemical Responses in Cancerous and Healthy Cell Models: 2025 IEEE 4th Colombian BioCAS Workshop
Muñoz, M., Garcia, V., Calvo, P. C., Fonthal, F., Perilla, S. Y., López-Molina, G., Jamaica-Franco, M. V., Ramírez-Prieto, J., Ondo-Méndez, A. & Rodríguez-Burbano, D. C., Dec 12 2025, p. 1-5. 5 p.Research output: Knowledge networks › Conference proceedings › peer-review
Prizes
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Semilleros de Investigación Inter-Universidades 2024-2
Rodriguez Burbano, D. C. (Recipient), Ondo Mendez, A. O. (Recipient) & López, G. (Recipient), Nov 7 2024
Prize
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Tercer Puesto Ponencia Oral Proyecto de Investigación
Rodriguez Burbano, D. C. (Recipient), Ondo Mendez, A. O. (Recipient), López, G. (Recipient) & Leguizamon Gutierrez, V. (Recipient), Nov 14 2024
Prize
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Activities
- 5 Oral presentations at specialized academic events
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Exploring nanomedicine as a strategy for tumor sensitization
Jamaica, M. V. (Organizer), López-Molina, G. (Organizer), Ochoa Paipilla, M. N. (Organizer), Hernandez Rodriguez, A. D. P. (Organizer), Ramirez Prieto, J. (Organizer), Guluma Escamilla, M. J. (Organizer), Bello , L. M. (Organizer), Leguizamon Gutierrez, V. (Organizer), Palacio, J. M. (Organizer), Machuca, S. (Organizer), Tovar-Romero, H. V. (Organizer), Sandoval Navia, J. (Organizer), Rodriguez Burbano, D. C. (Organizer) & Ondo Mendez, A. O. (Organizer)
May 7 2025Activity: Talk types › Oral presentations at specialized academic events
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Evaluation of Carbon-Based Fluorescent Nanoparticles as Potential Photosensitizers: Biological and Electrochemical Responses in Cancerous and Healthy Cell Models
Rodriguez Burbano, D. C. (Speaker), López-Molina, G. (Speaker), Jamaica, M. V. (Keynote speaker), Calvo, P. C. (Speaker), Ondo Mendez, A. O. (Speaker) & Fonthal, F. (Speaker)
Aug 27 2025 → Aug 29 2025Activity: Talk types › Oral presentations at specialized academic events
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Exploring nanomedicine as a strategy for tumor sensitization
Rodriguez Burbano, D. C. (Speaker), Ondo Mendez, A. O. (Speaker), Machuca, S. (Speaker), Ochoa Paipilla, M. N. (Speaker), Leguizamon Gutierrez, V. (Organizer), Bello , L. M. (Organizer), Hernandez Rodriguez, A. D. P. (Organizer) & Sandoval Espinosa, J. (Speaker)
Nov 7 2024Activity: Talk types › Oral presentations at specialized academic events